GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs6684514 | 1 | rs12038481 | chr1:156284815 | BGLAP | chr1:156182784-156213112:+ | 0.23 | 3.91 | 0.000109 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BLCA | cis | rs17030613 | 1 | rs12040988 | chr1:113173804 | ST7L | chr1:113066142-113162405:- | 0.41 | 5.91 | 7.39E-9 | Diastolic blood pressure;Blood pressure |
| BLCA | cis | rs6684514 | 1 | rs12041164 | chr1:156279811 | BGLAP | chr1:156182784-156213112:+ | 0.23 | 3.92 | 0.000107 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BLCA | cis | rs12045807 | 1 | rs12045807 | chr1:150584834 | HORMAD1 | chr1:150670542-150693352:- | 0.43 | 4.53 | 8.0E-6 | Congenital left-sided heart lesions |
| BLCA | cis | rs2275426 | 1 | rs12049588 | chr1:46472422 | CCDC163P | chr1:45960581-45965646:- | -0.34 | -6.43 | 3.87E-10 | Body mass index |
| BLCA | cis | rs7714584 | 1 | rs12054923 | chr5:150249059 | LOC134466 | chr5:150310000-150326146:- | 0.44 | 5.86 | 1.0E-8 | Crohn's disease |
| BLCA | cis | rs12091564 | 1 | rs12091564 | chr1:145395604 | NOTCH2NL | chr1:145209111-145295525:+ | -0.65 | -5.96 | 5.84E-9 | Coronary heart disease |
| BLCA | cis | rs6684514 | 1 | rs12117903 | chr1:156311165 | BGLAP | chr1:156182784-156213112:+ | 0.22 | 3.84 | 0.000145 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BLCA | cis | rs6684514 | 1 | rs12117951 | chr1:156305286 | BGLAP | chr1:156182784-156213112:+ | 0.23 | 3.88 | 0.000122 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BLCA | cis | rs17030613 | 1 | rs12120956 | chr1:113202571 | ST7L | chr1:113066142-113162405:- | 0.42 | 6.17 | 1.76E-9 | Diastolic blood pressure;Blood pressure |
| BLCA | cis | rs17030613 | 1 | rs12126971 | chr1:113231286 | ST7L | chr1:113066142-113162405:- | 0.41 | 6.03 | 3.93E-9 | Diastolic blood pressure;Blood pressure |
| BLCA | cis | rs17030613 | 1 | rs12130243 | chr1:113169667 | ST7L | chr1:113066142-113162405:- | 0.41 | 5.91 | 7.39E-9 | Diastolic blood pressure;Blood pressure |
| BLCA | cis | rs6684514 | 1 | rs12132919 | chr1:156318141 | BGLAP | chr1:156182784-156213112:+ | 0.23 | 3.88 | 0.000122 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |
| BLCA | cis | rs17030613 | 1 | rs12133583 | chr1:113240790 | ST7L | chr1:113066142-113162405:- | 0.43 | 6.24 | 1.13E-9 | Diastolic blood pressure;Blood pressure |
| BLCA | cis | rs6684514 | 1 | rs12134983 | chr1:156290409 | BGLAP | chr1:156182784-156213112:+ | 0.23 | 3.86 | 0.000132 | Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels |